Research

Opioid Prescribing

Pediatric Opioid Prescribing

  • Chua KP, Shrime MG, Conti RM. Effect of FDA investigation on opioid prescribing to children after tonsillectomy/adenoidectomy. Pediatrics. 2017;140(6): e20171765. PMID: 29146621
  • Chua KP, Brummett CM, Conti RM, Bohnert ASB. Association of opioid prescribing patterns with prescription opioid overdose in adolescents and young adults. JAMA Pediatr. 2020; 174(2): 141-148. PMID: 31841589. PMCID: PMC6990690
  • Chua KP, Brummett CM, Conti RM, Bohnert ASB. Opioid Prescribing to US Children and Young Adults in 2019. Pediatrics. 2021; 148(3):e2021051539. PMID: 34400571. PMCID: PMC8778996.
  • Chua KP, Thorne MC, Ng S, Donahue M, Brummett CM. Association between default number of opioid doses in electronic health record systems and opioid prescribing to adolescents and young adults undergoing tonsillectomy. JAMA Netw Open. 2022;5(6): e2219701. PMID: 35771572. PMCID: PMC9247741.
  • Chua KP, Brummett BM, Kelley-Quon LI, Bicket MC, Gunaseelan V, Waljee JF. Pediatric Surgical Opioid Prescribing by Procedure, 2020-2021. Pediatrics. 2024 Jun 26; doi:10.1542/peds.2024-065814. PMID: 38919985; PMCID: PMC11211692.

Opioid Prescribing Limits

  • Chua KP, Brummett CM, Waljee JF. Opioid prescribing limits for acute pain: potential problems with design and implementation. JAMA. 2019; 321(7):643-644. PMID: 30703214
  • Chua KP, Nguyen T, Waljee JF, Nalliah RP, Brummett CM. Association between state opioid prescribing limits and duration of opioid prescriptions from dentists. JAMA Netw Open. 2023;6(1):e2250409. PMID: 36630136. doi:10.1001/jamanetworkopen.2002.50409.

Dental Opioid Prescribing

  • Chua KP, Kenney B, Waljee JF, Nalliah RP, Brummett CM. Dental opioid prescriptions and overdose risk in patients and their families. Am J Prev Med. 2021; 61(2):165-173. PM. PMID: 33975766. PMCID: PMC8319034.
  • Chua KP, Hu H, Waljee JF, Brummett CM, Nalliah R. Opioid prescribing patterns by dental procedure among US privately and publicly insured patients, 2013 through 2018. JADA. 2021; 152(4):309-317. PMID: 33637299; PMCID: PMC8118387.
  • Chua KP, Waljee JF, Gunaseelan V, Nalliah RP, Brummett CM. Distribution of Opioid Prescribing and High-Risk Prescribing among U.S. Dentists in 2019. AJPM. 2022 Mar;62(3):317-325. PMID: 35190099. PMCID: PMC8867916.
  • Chua KP, Nguyen TD, Waljee JF, Nalliah RP, Brummett CM. Association Between State Opioid Prescribing Limits and Duration of Opioid Prescriptions From Dentists. JAMA Netw Open. 2023 Jan 3;6(1):e2250409. doi: 10.1001/jamanetworkopen.2022.50409. PMID: 36630136; PMCID: PMC9857382.

Surgical Opioid Prescribing

  • Chua KP, Waljee JF, Smith MA, Bahl S, Nalliah RP, Brummett CM. Estimation of the prevalence of delayed dispensing among opioid prescriptions from US surgeons and dentists. JAMA Netw Open. 2022 May 2;5(5): e2214311. PMID: 35622363. PMCID: PMC9142869.
  • Waljee JF, Gunaseelan V, Bicket MC, Brummett CM, Chua KP. Safety and Distribution of Opioid Prescribing among U.S. Surgeons in 2019. Ann Surg. 2023 Jan 19. doi:10.1097/SLA.0000000000005802.
  • Priest CR, Waljee JF, Bicket MC, Hu HM, Chua KP. Comparison of Opioids Prescribed by Advanced Practice Clinicians vs Surgeons After Surgical Procedures in the US. JAMA Netw Open. 2023 Jan 3;6(1):e2249378. doi: 10.1001/jamanetworkopen.2022.49378. PMID: 36598786; PMCID: PMC9857656.
  • Zhang J, Waljee JF, Nguyen TD, Bohnert ASB, Brummett CM, Bicket MC, Chua KP. Opioid Prescribing by US Surgeons, 2016-2022. JAMA Netw Open. 2023;6(12):e2346426. doi:10.001/jamanetworkopen.2023.46426. PMID: 38060230; PMCID: PMC10704275.
  • Chua KP, Nguyen TD, Brummett CM, Bohnert ASB, Gunaseelan V, Englesbe MJ, Lee S, Waljee JF. Association Between Prescription Drug Monitoring Program Use Mandate and Opioid Prescribing and Patient-Reported Outcomes After Surgery. Ann Surg. 2024 May 8. PMID: 38716667.

Other Opioid Prescribing

  • Chua KP, Brummett CM, Ng S, Bohnert ASB. Association Between Receipt of Overlapping Opioid and Benzodiazepine Prescriptions from Multiple Prescribers and Overdose Risk. JAMA Netw Open. 2021;4(8): e2120353. PMID: 34374769. PMCID: PMC8356065.
  • Chua KP, Perrone J, Redding LE, Brummett CM, Bahl S, Bohnert AS. Trends in the number of patients linked to potential vet-shopping behavior in the United States (2014-2019). Am J Vet Res. 2021; 83(2):147-152. PMID: 34941568

Medication for Opioid Use Disorder

  • Chua KP, Bicket MC, Bohnert ASB, Conti RM, Lagisetty P, Nguyen TD. Buprenorphine dispensing after elimination of the waiver requirement. NEJM 2024 Apr 25;390(16):1530-1532. PMID: 38657250. PMCID: PMC11103581.
  • Chua KP, Dahlem CH, Nguyen TD, Brummett CM, Conti RM, Dora-Laskey AD, Kocher KE. Naloxone and Buprenorphine Prescribing Following U.S. Emergency Department Visits for Suspected Opioid Overdose: August 2019-April 2021. Ann Emer Med. 2022; 79(3):225-236. PMID: 3480277.
  • Chua KP, Nguyen TD, Zhang J, Conti RM, Lagisetty P, Bohnert AS. Trends in Buprenorphine Initiation and Retention in the United States, 2016-2022. JAMA. 2023;329(16):1402–1404. doi:10.1001/jama.2023.1207. PubMED PMID: 37097363; PubMed Central PMCID: PMC10130945.
  • Chua KP, Conti RM, Lagisetty P, Bohnert ASB, Nuliyalu U, Nguyen TD. Association between cost-sharing and buprenorphine prescription dispensing. JGIM. 2024 Jun 18; doi:10.1007/s11606-024-08819-2. PMID: 38888865.

Pediatric Health Care and Policies

  • Chua KP, Conti RM, Freed GA. Appropriately framing child health care spending – a pre-requisite for value improvement. JAMA. 2018; 319(11):1087-1088. PMID: 29482195
  • Chua KP, Volerman A, Zhang J, Hua J, Conti RM. Antidepressant Dispensing to US Adolescents and Young Adults: 2016-2022. Pediatrics. 2024 Mar 1;153(3). doi: 10.1542/peds.2023-064245. PMID: 38404197; PMCID: PMC10904889.
  • Chua KP, Volerman A, Conti RM. Prescription drug dispensing to U.S. children during the COVID-19 Pandemic. Pediatrics. 2021: e211460. PMID: 34285080. PMCID: PMC8344340.
  • He S, McCabe SE, Conti RM, Volerman A, Chua KP. Prescription stimulant dispensing to US children: 2017-2023. Pediatrics. 2025; e2024068558.
  • Lee JM, Sharifi M, Oshman L, Griauzde DH, Chua KP. Dispensing of Glucagon-Like Peptide-1 Receptor Agonists to Adolescents and Young Adults, 2020-2023. JAMA. 2024 May 22: doi: 10.1001/jama.2024.7112. PMID: 38776113; PMCID: PMC11112492.
  • Chua KP, Schuster MA, McWilliams JM. Differences in health care access and utilization between older adolescents and young adults with asthma. Pediatrics. 2013;131(5):892-901. PMID: 23610211. PMCID: PMC4074656.
  • Chua KP, Sommers BD. Changes in health and medical spending among young adults under health reform. JAMA. 2014;311(23):2437-2439. PMID: 24938568.

Out-of-pocket Spending

  • Chua KP, Conti RM, Lagisetty P, Bohnert ASB, He S, Nguyen TD. Association between cost-sharing and naloxone prescription dispensing. JAMA. 2024; doi:10.1001/jama.2024.8378.
  • Chua KP, Conti RM. Out-of-pocket spending among commercially insured patients for epinephrine autoinjectors between 2007 and 2014. JAMA Intern Med. 2017; 177(5):736-739. PMID: 28346591. PMCID: PMC5377880
  • Chua KP, Lee JM, Conti RM. Out-of-pocket spending for insulin and other health care services among privately insured patients with type 1 diabetes. JAMA Intern Med. 2020; 180(7):1012-1014. PMID: 32478819. PMCID: PMC7265118.
  • Chua KP, Fendrick AM, Conti RM, Moniz MM. Out-of-pocket spending for deliveries and newborn hospitalizations among the privately insured. Pediatrics. 2021; e2021050552. PMID: 34140392
  • Chua KP, Conti RM, Becker NV. Assessment of Out-of-Pocket Spending for COVID-19 Hospitalizations in the U.S. in 2020. JAMA Netw Open. 2021;4(10): e2129894. PMCID: PMC8524307. PMID: 34661662
  • Carlton EF, Becker NV, Moniz MH, Scott JW, Prescott HC, Chua KP. Out-of-Pocket Spending for Non-Birth-Related Hospitalizations of Privately Insured US Children, 2017 to 2019. JAMA Pediatr. 2023 May 1;177(5):516-525. doi: 10.1001/jamapediatrics.2023.0130. PMID: 36972040; PMCID: PMC10043803.
  • Chua KP, Conti RM, Lagisetty P, Bohnert ASB, He S, Nguyen TD. Association between cost-sharing and naloxone prescription dispensing. JAMA. 2024 June 13; doi:10.1001/jama.2024.8378. PMID: 38869887, PMCID: PMC11177218.

Low-value Care

  • Chua KP, Schwartz AL, Volerman A, Conti RM, Huang ES. Use of low-value pediatric services among the commercially insured. Pediatrics. 2016; 138(6): e20161809. PMID: 27940698. PMCID: PMC5127068
  • Chua KP, Fischer MA, Linder JA. Appropriateness of outpatient antibiotic prescribing among privately insured US patients: ICD-10-CM based cross sectional study. BMJ. 2019;364: k5092. PMID: 30651273. PMCID: PMC6334180
  • Chua KP, Conti RM, Becker NV. U.S. insurer spending on ivermectin prescriptions for COVID-19. JAMA. 2022 Feb 8;327(6):584-587. PMID: 35024763.
  • Chua KP, Fischer MA, Rahman M, Linder JA. Changes in the appropriateness of US outpatient antibiotic prescribing after the Coronavirus disease 2019 outbreak: an interrupted time series analysis of 2017-2021 data. CID. 2024 Apr 22; doi: 10.1093/cid/ciae135. PMID: 38648159.

Orphan Drugs

  • Kimmel L, Conti RM, Volerman A, Chua KP. Pediatric orphan drug indications: 2010- 2018. Pediatrics 2020; 145(4): e20193128. PMID: 32127360. PMCID: PMC7111489.
  • Chua KP, Conti RM. Policy implications of orphan drug designation for remdesivir to treat COVID-19. JAMA Intern Med. 2020; 180(10): 1273-1274. PMID: 32804187
  • Chua KP, Kimmel L, Conti RM. Spending for orphan indications among top-selling orphan drugs approved to treat common diseases. Health Affairs. 2021; 40(3): 453-460. PMID: 33646878; PMCID: PMC8011952.